A recombinant HSV-1 virus expressing EGFP from the HCMV major immediate early promoter (KOS-CMVGFP) was constructed to monitor viral replication and spread in vitro and in mice. Transmission of HSV-2 has become a major health concern, since it has been shown to promote transmission of other sexually transmitted diseases. In an effort to modify FcγR activity without affecting other gE functions, we constructed a mutant virus, NS-gE339, that has four amino acids inserted into gE within the domain homologous to mammalian IgG FcγRs. Full text Full text is available as a scanned copy of the original print version. Full Text The Full Text of this article is available as a PDF (149K). Based on conservation between human and mouse NK complexes, the data predict the presence of a human Rhs1 orthologue on chromosome 12p12–13. Kalman CM, Laskin OL.
Herpes simplex virus has developed many strategies for survival in the human host. Additional compounds used to treat HSV infections are famciclovir, the prodrug of penciclovir; ganciclovir; foscarnet; and cidofovir. These results are discussed in the light of previous experience with TK-deficient viruses. Habif TP. Clinical Dermatology. HSV establishes lifelong latent infection in the sensory ganglia after resolution of acute infection. aureus; the skin infection resolved after treatment with oral antibiotics; however one man experienced 2 recurrences in the same area.
p. 454-90 4. Lautenschlager S, Stockfleth E. Human herpes viruses. In: Burgdorf WHC, Plewig G, Wolff HH, Landthaler M, editors. She received treatment with intravenous acyclovir 10 mg/kg every 8 hours. 3 rd ed.
Heidelberg: Springer Medizin Verilag; 2009. p. 74-92. 5. Moreover, we demonstrate that treatment of mice with either mAb 1A8 or mAb RB6-8C5 induced systemic neutropenia, however only depletion of Gr-1+ cells was associated with increased virus replication and enhanced lesion severity in the zosteriform model. Essentials in Dermatology. 2 nd ed.
New Delhi: Jaypee Brothers Medical Publishers Pvt. Ltd; 2009. p. 43-56. In addition, hypergranulosis of the epidermis and vacuolar degeneration in the basal layer is observed. Koh MJ, Seah PP, Teo RY. Zosteriform herpes simplex.
Singapore Med J 2008;49:e59-60.